Design Automation Methods and Tools for Microfluidics-Based by Fei Su, Krishnendu Chakrabarty (auth.), Krishnendu PDF

By Fei Su, Krishnendu Chakrabarty (auth.), Krishnendu Chakrabarty, Jun Zeng (eds.)

ISBN-10: 1402051220

ISBN-13: 9781402051227

ISBN-10: 1402051239

ISBN-13: 9781402051234

Microfluidics-based biochips, sometimes called lab-on-a-chip or bio-MEMS, have gotten more and more renowned for DNA research, scientific diagnostics, and the detection/manipulation of bio-molecules. because the use of microfluidics-based biochips raises, their complexity is predicted to develop into major a result of want for a number of and concurrent assays at the chip, in addition to extra refined keep an eye on mechanisms for source administration. Time-to-market and fault tolerance also are anticipated to turn out to be layout issues. therefore, present full-custom layout ideas won't scale good for greater designs. there's a have to carry an identical point of CAD aid to the biochip fashion designer that the semiconductor now takes for granted.

Design Automation tools and instruments for Microfluidics-Based Biochips offers with all points of layout automation for microfluidics-based biochips. specialists have contributed chapters on a number of points of biochip layout automation. themes contain equipment modeling; version of bioassays for on-chip implementations; numerical equipment and simulation instruments; architectural synthesis, scheduling and binding of assay operations; actual layout and module placement; fault modeling and trying out; reconfiguration methods.

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Extra info for Design Automation Methods and Tools for Microfluidics-Based Biochips

Example text

From time t=0+ to τ, DEP fusion of droplets A and B occur at E4. The internal circulation inside droplet AB promotes the first stage of the chemical reaction producing C. E4 is turned OFF once the fusion of droplets A and B is accomplished. At time t=2τ, E3 is turned ON and fusion of droplets ABC and D occurs at E3. The mixing of chemicals inside droplet ABCD enables the reaction between chemicals C and D to produce chemical E. Snapshots of the transient process described above are obtained from simulation and shown in Fig.

H. A. Pohl, Dielectrophoreisis: The behavior of neutral matter in nonuniform electric fields, (Cambridge University Press, Cambridge, 1978). A. Desai, S. W. Lee and Y. C. Tai, A MEMS electrostatic particle transportation system, MEMS 1998 (1998). -B. Wang, J. Vykoukal, F. F. Becker and P R. C. Gascoyne P. R. , 74, 289-2701 (1998). Modeling and Simulation of Electrified Droplets 51 23. P. R. C. Gascoyne and J. Vykoukal, Particle separation by dielectrophoresis, Electrophoresis, 23, 1973-1983 (2002).

Design Automation Methods and Tools for Microfluidics-Based Biochips, 53–84. © 2006 Springer. 54 Chapter 3 dictated by contamination concerns in biology and medicine.

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Design Automation Methods and Tools for Microfluidics-Based Biochips by Fei Su, Krishnendu Chakrabarty (auth.), Krishnendu Chakrabarty, Jun Zeng (eds.)


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