By Michael F Greene, Robert K. Creasy MD, Robert Resnik MD, Jay D. Iams MD, Charles J. Lockwood MD, Thomas Moore MD
On your perform, you require complicated wisdom of the obstetrical, scientific, genetic and surgical problems of being pregnant and their results at the mom and fetus. With either simple technology and scientific details, six new chapters, and an up-to-date colour layout, you would like glance no additional than the sixth variation of this long-time most sensible vendor. thoroughly revised and up to date, this well known reference now's an entire on-line source due to the extra performance of specialist seek advice - www.expertconsult.com.Includes either easy technology and medical details to provide you finished wisdom of the biology of pregnancy.Acts as a good source for OB/GYNs learning for his or her Maternal-Fetal drugs forums - and for practitioners who desire easy access to sensible information.Features a significant other web site at www.expertconsult.com with totally searchable text.Provides an up to date and targeted reference record to maintain you brand new at the criteria of care in maternal-fetal drugs today.Keeps you present with a brand new part: problems on the Maternal-Fetal Interface.and 6 new chapters: Biology of Parturition, Developmental Origins of future health and affliction, Intrapartum review of Fetal healthiness, Pathogenesis of Pre-term start, Maternal and Fetal Infectious problems, and Benign Gynecological stipulations of Pregnancy.Features over 50% new authorship with elevated specialise in foreign perspectives.Includes the next sizzling themes in Maternal-Fetal drugs: o Biology of Parturitiono Fetal Growtho Prenatal Genetic Screening and Diagnosiso Fetal Cardiac Malformations and Arrhythmias o Thyroid illness and being pregnant o administration of melancholy and Psychoses while pregnant and the PuerperiumFocuses on proof established medication, the present top perform in MFM for diagnosing and treating excessive danger pregnancies.Includes new illustrations and an up to date, colour design.Your buy entitles you to entry the website till the following variation is released, or till the present version isn't any longer provided on the market via Elsevier, whichever happens first. If the following version is released lower than 12 months after your buy, you may be entitled to on-line entry for 365 days out of your date of buy. Elsevier reserves the proper to provide an appropriate alternative product (such as a downloadable or CD-ROM-based digital model) should still entry to the website be discontinued.
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Additional resources for Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice: (Expert Consult - Online and Print) (MATERNAL-FETAL MEDICINE (CREASY)), 6th Edition
Another explanation could be that inversions involving relatively short DNA sequences may not be involved in crossing over. TRANSLOCATIONS A translocation is the most common form of chromosome structural rearrangement in humans. There are two types: reciprocal (Fig. 1-21) and robertsonian (Fig. 1-22). Reciprocal Translocation. If a reciprocal translocation is balanced, phenotypic abnormalities are uncommon. Unbalanced trans- CHAPTER 1 locations result in miscarriage, stillbirth, or live birth with multiple malformations, developmental delay, and mental retardation.
Abnormalities of the sex chromosomes or genes on the sex chromosomes may affect any of the stages of sexual and reproductive development. Although an increased number of either the X or the Y chromosome enhances the likelihood of mental retardation and other anatomic anomalies, irrespective of the sex phenotype, aneuploidy of the sex chromosome does not alter prenatal fetal development nearly as much as aneuploidy of an autosome. Of note, many mutations or deletions in the X chromosome do result in X-linked mental retardation.
If the affected female is homozygous, all her children will be affected. 3. The incidence of X-linked dominant disease may be twice as common in females as in males. Some rare disorders that are exclusively or nearly exclusively seen in females, such as Rett syndrome and incontinentia pigmenti type 2, appear to be X-linked dominant conditions in which affected males die before birth. 1 2 1 2 5 3 6 4 5 6 FIGURE 1-29 Stereotypical pedigree of X-linked dominant inheritance. Affected males have no affected sons and no normal daughters.
Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice: (Expert Consult - Online and Print) (MATERNAL-FETAL MEDICINE (CREASY)), 6th Edition by Michael F Greene, Robert K. Creasy MD, Robert Resnik MD, Jay D. Iams MD, Charles J. Lockwood MD, Thomas Moore MD