Comparative Physiology of the Vertebrate Kidney - download pdf or read online

By William H. Dantzler

ISBN-10: 1493937324

ISBN-13: 9781493937325

ISBN-10: 1493937340

ISBN-13: 9781493937349

This moment variation bargains a complete evaluation of the physiological services of vertebrate kidneys from a comparative perspective, with specific emphasis on nonmammalian vertebrates. the themes coated comprise renal constitution; glomerular ultrafiltration; tubular delivery of inorganic ions, natural ingredients, and fluid; and urine dilution and focus. Mammalian renal functionality is simply thought of for reasons of comparability with nonmammalian renal functionality and as a body of reference for a few of the discussions. the main findings on nonmammalian renal functionality and the real unanswered questions raised by way of these findings are defined intimately. As such, the e-book offers entire info on comparative renal functionality for organic scientists and complex scholars of biology with a few wisdom of body structure and a wish to understand extra approximately renal functionality in vertebrates, and for mammalian renal physiologists who desire to receive a broader view of renal function.

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Extra info for Comparative Physiology of the Vertebrate Kidney

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J Ultrastruct Res 32:526–544 Latta H, Johnston WH, Stanley TM (1975) Sialoglycoproteins and filtration barriers in the glomerular capillary wall. J Ultrastruct Res 51:354–376 References 35 Liu W, Morimoto T, Kondo Y, Iinuma K, Uchida S, Imai M (2001) “Avian-type” renal medullary tubule organization causes immaturity of urine-concentrating ability in neonates. Kidney Int 60:680–693 Logan AG, Moriarty RJ, Morris R, Rankin JC (1980) The anatomy and blood system of the kidney in the river lamprey, Lampetra fluviatilis.

2012). These details have yet to be studied in representatives of other vertebrate classes. The basement membrane, the middle component of the filtration barrier, has generally been shown in electron micrographs to consist of a central electron-dense layer, the lamina densa, with two much thinner electron-lucent layers on either side of it, the lamina rara interna and the lamina rara externa (Fig. 12) (Nielsen et al. 2012). Although the lamina densa clearly exists and appears to reflect a true basement membrane, a number of studies on mammals have indicated that the two laminae rarae are artifacts of fixation and that the three-layer structure of the basement membrane does not exist (Chan et al.

Because the ultrafiltration coefficient is the product of the capillary area available for filtration and the capillary hydraulic conductivity, the difference between the values for amphibians and mammals may result primarily from an apparently greater area available for filtration in amphibian than in mammalian glomeruli (Renkin and Gilmore 1973) rather than from a difference in hydraulic conductivities. Unfortunately, as noted above, there are no really accurate measurements of the glomerular capillary area available for filtration, much less the area actually used, in any species.

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Comparative Physiology of the Vertebrate Kidney by William H. Dantzler


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