Download e-book for kindle: Clinical Proteomics: Methods and Protocols by Young-Ki Paik, Hoguen Kim, Eun-Young Lee, Min-Seok Kwon,

By Young-Ki Paik, Hoguen Kim, Eun-Young Lee, Min-Seok Kwon, Sang Yun Cho (auth.), Antonia Vlahou (eds.)

ISBN-10: 158829837X

ISBN-13: 9781588298379

The box of scientific proteomics has quickly developed prior to now few years and is constantly growing to be as new methodologies and applied sciences emerge. In Clinical Proteomics, a opt for crew of major researchers has contributed their state of the art methodologies on protein profiling and identity of affliction biomarkers in tissues, microdissected cells and physique fluids. Experimental methods regarding the applying of two-dimensional electrophoresis, multi-dimensional liquid chromatography, SELDI/MALDI mass spectrometry and protein arrays, in addition to the bioinformatic and statistical instruments pertinent to the research of proteomics facts, are completely unique in those without difficulty reproducible equipment and protocols, defined in the course of the step by step educational layout of the hugely winning Methods in Molecular Biology™ series.

With its multi-disciplinary process, Clinical Proteomics provides built-in, state of the art concepts guaranteed to be useful to quite a lot of researchers together with clinicians, molecular biologists, chemists, bioinformaticians and computational biologists.

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Additional info for Clinical Proteomics: Methods and Protocols

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Mol. Cell Proteomics 5, 1760–1771. 16. , and Lindahl, M. (2006) Comparative proteomics of nasal fluid in seasonal allergic rhinitis. J. Proteome Res. 5, 330–338. 17. Koo, B. , Lee, D. , Ha, H. , Kim, J. , and Kim, C. W. (2005) Comparative analysis of the tear protein expression in blepharitis patients using two-dimensional electrophoresis. J. Proteome Res. 4, 719–724. 18. Grus, F. , Podust, V. , Dalmasso, E. , and Pfeiffer, N. (2005) SELDI-TOF-MS ProteinChip array profiling of tears from patients with dry eye.

And Kros, J. M. (2003) Identification of tumor-related proteins by proteomic analysis of cerebrospinal fluid from patients with primary brain tumors. J. Neuropathol. Exp. Neurol. 62, 855–862. Gibson, D. , and Rooney, M. E. (2006) Proteomic analysis of recurrent joint inflammation in juvenile idiopathic arthritis. J. Proteome Res. 5, 1988–1995. , and Lenter, M. C. (2005) Proteomic study of human bronchoalveolar lavage fluids from smokers with chronic obstructive pulmonary disease by combining surface-enhanced laser desorption/ionization-mass spectrometry profiling with mass spectrometric protein identification.

3rd, Liotta, L. , and Veenstra, T. D. (2005) Cancer proteomics: many technologies, one goal. Expert Rev. Proteomics 2, 693–703. 54. Schrader, M. and Selle, H. (2006) The process chain for peptidomic biomarker discovery. Dis. Markers 22, 27–37. 55. Danna, E. A. and Nolan, G. P. (2006) Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level. Curr. Opin. Chem. Biol. 10, 20–27. 56. , Tosti, M. , and Mele, A. (2005) Screening for hepatocellular carcinoma. Dig. Liver Dis.

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Clinical Proteomics: Methods and Protocols by Young-Ki Paik, Hoguen Kim, Eun-Young Lee, Min-Seok Kwon, Sang Yun Cho (auth.), Antonia Vlahou (eds.)

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