Download PDF by Clinical Evidence: Clinical Evidence: Cardiovascular Disorders ; The

By Clinical Evidence

ISBN-10: 0727917889

ISBN-13: 9780727917881

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Additional resources for Clinical Evidence: Cardiovascular Disorders ; The International Source of the Best Available Evidence for Cardiovascular Health Care

Example text

Recurrent chest pain, silent ischaemia, haemodynamic instability). To relieve pain and ischaemia; to prevent death and myocardial infarction; to identify people at high AIMS OF INTERVENTION risk who require revascularisation; to facilitate early hospital discharge in people at low and medium risk; to modify risk factors; to prevent death, myocardial infarction, and recurrent ischaemia after discharge from hospital, with minimum adverse effects. OUTCOMES Rate of death or myocardial infarction (often measured at 2, 7, and 30 days, and 6 months after randomisation); and adverse effects of treatment.

7 Propafenone . . . . . . . 10 Unknown effectiveness Amiodarone . . . . . . . . 5 DC cardioversion. . . . . . . 5 Quinidine. . . . . . . . . 14 Sotalol . . . . . . . . . 15 Unlikely to be beneficial Digoxin . . . . . . . . . . 6 Verapamil . . . . . . . . 15 RATE CONTROL Likely to be beneficial Digoxin . . . . . . . . . 15 Diltiazem . . . . . . . . . 16 Timolol . . . . . . . . . 17 Verapamil . . . . . . . . 18 Unknown effectiveness Amiodarone .

One RCT found that propafenone increased conversion to sinus rhythm after 8 hours compared with amiodarone. One RCT found no significant difference between conversion to sinus rhythm between amiodarone and propafenone at 1 hour. One RCT found no significant difference in conversion to sinus rhythm between propafenone and digoxin at 1 hour. Three RCTs found insufficient evidence to compare rates of conversion to sinus rhythm between propafenone and flecainide. Propafenone and flecainide are not used in people with known or suspected ischaemic heart disease because they may cause arrhythmias.

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Clinical Evidence: Cardiovascular Disorders ; The International Source of the Best Available Evidence for Cardiovascular Health Care by Clinical Evidence


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