CHRONOPHARMACEUTICS - Science and Technology for Biological by Bi-Botti C. Youan PDF

By Bi-Botti C. Youan

ISBN-10: 0471743437

ISBN-13: 9780471743439

Chronopharmaceutics

Science and know-how for organic Rhythm Guided remedy and Prevention of Diseases

Edited via

Bi-Botti C. Youan

The first general reference on chronopharmaceutics

As we greater know how organic techniques spread in actual time via advances in chronobiology and comparable fields, we will create more secure, more advantageous medicines, drug supply platforms, and sickness tracking and prevention structures. while administered in right coordination with a patient's physique rhythms, such medicinal drugs can maximize healing end result whereas minimizing negative effects. Chronopharmaceutics provides the 1st commonplace reference textual content in this rising cross-disciplinary box and its power for healing and preventive medicine.

Bringing jointly the most recent findings from skilled investigators, this edited paintings provides a much-needed unmarried resource on chronopharmaceutics. After an advent that features a timeline of key discoveries, an outline of regula-tory, formula, production and key source matters linked to chronopharmaceutics, the special assurance examines:

  • Chronopharmacokinetics

  • Chronotherapy

  • Controlled unlock platforms caused by way of actual and/or chemical activation

  • Chronopharmacodynamics, chronomics, and anesthesia

  • Markers-guided chronotheranostics

Filling a spot in either the graduate lecture room and the operating commercial or study laboratory, Chronopharmaceutics bargains scholars, teachers, and execs a distinct and entire reference for this state of the art box.

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The rhythm disturbances also characterize hematologic and immune related disease states, like, infection [261, 262]. , herpes) were reviewed [263]. Another example of viral diseases with biological rhythm is acquired immune deficiency syndrome (AIDS) [264]. 5 BIOLOGICAL RHYTHMS, HEALTH, AND DISEASES 21 suggested that circulating virus concentrations also vary in a diurnal fashion, as well as nonperiodically, a mathematical model has been developed to provide the first demonstration of diurnal variations in AIDS patients [265].

2 Chronopharmaceutical Drug Delivery Systems for Oral Route . . 3 Chronopharmaceutical Drug Delivery Systems for Transdermal Route . . . . . . . . . . . . . . . . . . 4 Chronoprevention Systems of Diseases: Chronotheranostics. . . 2 2 4 4 16 16 17 17 18 19 19 20 22 23 23 23 24 25 29 30 Chronopharmaceutics: Science and Technology for Biological Rhythm-Guided Therapy and Prevention of Diseases, edited by Bi-Botti C. Youan Copyright r 2009 John Wiley & Sons, Inc.

Introduction to Chronopharmaceutics . . . . . . . . . . . . . . Definition and Concept of Chronopharmaceutics . . . . . . . . . . Chronology of Chronotherapy and Related Concepts: Foundation for Chronopharmaceutics. . . . . . . . . . . . . . . . . . . . 5 Biological Rhythms, Health, and Diseases . . . . . . . . . . . . 1 Biological Rhythms and Sleep Disorders. . . . . . . . . . 2 Biological Rhythms and Respiratory Diseases.

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CHRONOPHARMACEUTICS - Science and Technology for Biological Rhythm-Guided Therapy and Prevention of by Bi-Botti C. Youan


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